The CEO AI Podcast

The CEO AI Podcast by Gary Ambrosino is the go-to audio destination for CEOs, founders, board members, and C-level executives navigating the transformative power of artificial intelligence in fast-growth businesses. Each episode is a strategic, no-fluff conversation designed specifically for decision-makers who need to understand and implement AI right now—not in theory, but in practice. Whether you’re an executive at a scaling SaaS startup, a PE-backed portfolio company, or a growth-stage enterprise undergoing digital transformation, this podcast gives you the frameworks, case studies, and tactical insights to lead with confidence in the age of AI. Host Gary Ambrosino—a veteran tech CEO, board member, and AI entrepreneur—breaks down the essential differences between “AI Forward” and “AI First” strategies, helping executives identify where their organizations sit in the AI adoption curve and how to advance to the next level. You’ll hear from AI innovators, operational leaders, and enterprise strategists as they share how AI is being used in product development, customer success, go-to-market strategies, operations, cybersecurity, investor relations, and more. Topics covered include: • Building an AI-first executive mindset • Leveraging generative AI for competitive advantage • AI governance, regulation, and ethical risk mitigation • Automation and operational efficiency at scale • Using AI in strategic planning and board reporting • Recruiting and leading AI-ready teams • Transitioning legacy workflows to intelligent automation • How to pitch, justify, and implement AI initiatives inside your company Each episode is designed to fit into a busy executive schedule—concise, information-rich, and immediately actionable. Whether you’re just starting to explore AI integration or already deploying AI solutions at scale, you’ll find immense value in this curated collection of interviews, insights, and real-world applications. Who is this podcast for? • CEOs, COOs, CTOs, CIOs, and CFOs looking to drive ROI from AI • Board members and investors evaluating AI initiatives • Growth-stage company executives responsible for innovation • Strategy, operations, and transformation leaders in tech, finance, healthcare, logistics, and other dynamic sectors If you’re looking to move beyond the hype and get real about what AI can do for your business today, this podcast is for you. Subscribe to The CEO AI Podcast and join the growing community of executive leaders using artificial intelligence to accelerate growth, unlock new revenue, and future-proof their organizations. Listen on Apple Podcasts, Spotify, Google Podcasts, or your favorite podcast platform. New episodes weekly.

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Episodes

9 hours ago

This report sets out to compile foundational trends related to Artificial Intelligence. One of the key takeaways is the unprecedented rate at which the world is changing due to rapid and transformative technology innovation and adoption, particularly in AI. The pace of change seems faster than ever, and AI User, Usage, and Capital Expenditure Growth are indeed highlighted as unprecedented.
Driving this momentum is significant investment. Big technology companies are generating loads of cash, which they are increasingly directing towards AI efforts to drive growth and fend off competitors. Capital Expenditure (CapEx) spending by major tech companies has been on the rise for years, accelerating with AI's prominence. This spend is primarily driven by the need for compute to train and run AI models. Data centers are a key beneficiary of this massive AI CapEx spend, with construction happening at speeds resembling consumer tech cycles more than traditional real estate development.
AI's impact is broad and varied. AI usage is surging among consumers, developers, enterprises, and governments globally. Consumer adoption is unprecedented, with platforms like ChatGPT showing incredibly rapid user growth compared to past technologies. The report also details AI rollouts by tech incumbents across their massive user bases, from Microsoft Copilot chats to Meta AI users and Google's Gemini and AI Overviews.
Beyond the digital realm, AI is also ramping up rapidly in the physical world, becoming data-driven in areas like autonomous taxis, mining exploration, and agriculture. The expansion of low-cost satellite internet is enabling AI-native experiences for a new wave of global internet users, potentially bypassing traditional app ecosystems.
The AI market is characterized by rising competition among traditional tech companies, emerging attackers, and even sovereign nations. There's a rapid release of new AI models, including large-scale multimodal and language models. The performance gap between closed and open-source models is closing, leading to an explosion of usage by developers as falling token costs make powerful models more accessible. Geopolitical competition is acute, particularly between China and the USA, with China demonstrating rapid relevance and catching up in model performance.
Finally, regarding the impact on the workforce, a key message from the report, quoting NVIDIA CEO Jensen Huang, is that "you're not going to lose… your job to an AI… but you're going to lose your job to somebody who uses AI." AI is expected to affect every job, creating some while eliminating others, but ultimately transforming all. Companies like Shopify are already seeing reflexive AI usage as a baseline expectation for employees. AI is presented as a potential opportunity to close the technology divide and increase global GDP.
This report paints a picture of accelerating innovation, massive investment, and widespread adoption that is fundamentally reshaping technology and society.

12 hours ago

This report sets out to compile foundational trends related to Artificial Intelligence. One of the key takeaways is the unprecedented rate at which the world is changing due to rapid and transformative technology innovation and adoption, particularly in AI. The pace of change seems faster than ever, and AI User, Usage, and Capital Expenditure Growth are indeed highlighted as unprecedented.
Driving this momentum is significant investment. Big technology companies are generating loads of cash, which they are increasingly directing towards AI efforts to drive growth and fend off competitors. Capital Expenditure (CapEx) spending by major tech companies has been on the rise for years, accelerating with AI's prominence. This spend is primarily driven by the need for compute to train and run AI models. Data centers are a key beneficiary of this massive AI CapEx spend, with construction happening at speeds resembling consumer tech cycles more than traditional real estate development.
AI's impact is broad and varied. AI usage is surging among consumers, developers, enterprises, and governments globally. Consumer adoption is unprecedented, with platforms like ChatGPT showing incredibly rapid user growth compared to past technologies. The report also details AI rollouts by tech incumbents across their massive user bases, from Microsoft Copilot chats to Meta AI users and Google's Gemini and AI Overviews.
Beyond the digital realm, AI is also ramping up rapidly in the physical world, becoming data-driven in areas like autonomous taxis, mining exploration, and agriculture. The expansion of low-cost satellite internet is enabling AI-native experiences for a new wave of global internet users, potentially bypassing traditional app ecosystems.
The AI market is characterized by rising competition among traditional tech companies, emerging attackers, and even sovereign nations. There's a rapid release of new AI models, including large-scale multimodal and language models. The performance gap between closed and open-source models is closing, leading to an explosion of usage by developers as falling token costs make powerful models more accessible. Geopolitical competition is acute, particularly between China and the USA, with China demonstrating rapid relevance and catching up in model performance.
Finally, regarding the impact on the workforce, a key message from the report, quoting NVIDIA CEO Jensen Huang, is that "you're not going to lose… your job to an AI… but you're going to lose your job to somebody who uses AI." AI is expected to affect every job, creating some while eliminating others, but ultimately transforming all. Companies like Shopify are already seeing reflexive AI usage as a baseline expectation for employees. AI is presented as a potential opportunity to close the technology divide and increase global GDP.
This report paints a picture of accelerating innovation, massive investment, and widespread adoption that is fundamentally reshaping technology and society.

2 days ago

 In this episode, we explore the insightful book "Empire of AI: Dreams and Nightmares in Sam Altman's Open AI" by Karen Hau. This book examines the internal conflicts within OpenAI, highlighting the tension between its original mission for AGI safety and its current commercial ambitions.
We discuss how OpenAI's transformation from a non-profit to a commercially driven entity is influenced by significant financial pressures, including a major investment from Microsoft. This episode serves as a cautionary tale about mission drift, emphasizing the importance of strong governance and awareness of ethical and social impacts amidst rapid technological advancements.

3 days ago

Welcome to the CEO AI Podcast, where today's discussion focuses on resilience and how setbacks can become the driving force for success, especially in the AI-driven business world. We explore "The Art of Bouncing Back," authored by Darlene Santor, also known as Coach Dar.
Coach Dar leverages her extensive experience as an occupational therapist and motivational speaker, focusing on high-pressure environments with pro athletes and Fortune 100 executives. Her book is a guide to finding one's flow after life challenges.
Discover how setbacks, rather than being seen as failures, are the norm in ambitious pursuits and how comebacks can refine one's journey. The episode delves into nine principles outlined by Coach Dar, including embracing the current state, understanding personal strengths, seeking feedback, leveraging emotional intelligence, and cultivating grit.
Through personal narratives and client stories, the episode offers valuable insights for CEOs looking to foster resilience and peak performance in their teams and themselves, utilizing intentional environments and emotional intelligence. Listen in for practical advice on building a culture that thrives on consistent resilience and relentless effort.

4 days ago

Google made the internet searchable. AI is making it actionable. In this episode, we explore the seismic shift from keyword search to intelligent agents—what it means for business, behavior, and the future of the web. From SEO to LLMs, from PageRank to prompt engineering, this is the real revolution in how humans find, decide, and act online. If you're building, investing, or operating in tech, you can't afford to miss this.
 

5 days ago

In this episode of the CEO AI podcast, we delve into Mustafa Suleiman's book "The Coming Wave," exploring the crucial roles AI and synthetic biology are playing in shaping our future. Discussing technological waves throughout history, the episode highlights how emerging technologies today not only follow historical patterns but also introduce unique challenges through their interconnected nature.We examine Suleiman's argument that current tech advancements represent both unprecedented potential and significant risks, emphasizing the urgency of implementing effective containment strategies. Topics include the evolution of technology, such as AI's relentless cognitive progress and synthetic biology's programmable nature, raising ethical and safety concerns.Moreover, the podcast brings attention to the impact on businesses, urging CEOs to incorporate safety, robust risk management, and purposeful leadership rather than merely adopting innovations. Real-world applications and potential futures are discussed, encouraging listeners to consider profound responsibilities accompanying such transformative tools.

6 days ago

In this episode of the CEO AI podcast's "Deep Dive," we delve into Gary Ambrosino's compelling article, "Is AI Eating Itself? The Future of AI Reliability?" The discussion highlights a growing concern in artificial intelligence: the potential crisis of AI models being trained predominantly on machine-generated data rather than original human content. As we explore the concept of "AI eating itself," we examine the risks associated with synthetic data feeding back into AI systems, leading to reduced accuracy and model collapse.
Discover how this phenomenon could dramatically impact the quality and trustworthiness of online information, as AI tools become entrenched in a loop of self-generated content, potentially reaching a point where trusted human-made data becomes scarce. With predictions that AI-generated content could dominate the web in the near future, this episode underscores the importance of data integrity and authenticity.
We discuss potential solutions, emphasizing the critical role of high-quality, verified training data and innovative methods to avert model collapse. Whether it involves diversified data sources or specialized agentic AI systems, the focus is on maintaining a strong foundation of human-authored knowledge to support AI development.
Join us as we explore these challenges and opportunities, offering strategic insights into maintaining reliability in AI systems amidst a sea of synthetic information.

6 days ago

In this detailed exploration of Stephen Brill's compelling book, "The Death of Truth," we delve into the erosion of truth in today's digital landscape. The episode dissects the central thesis that the decline of truth has led to a significant collapse of trust, making individuals more vulnerable to manipulation and deceit.The discussion highlights several key factors driving this erosion, including the role of engagement-focused algorithms, programmatic advertising, and social media business models. The episode also touches on the potential threats posed by generative AI, capable of creating sophisticated misinformation at an unprecedented scale.Listeners are encouraged to consider the profound impact on trust in institutions, political polarization, public health misinformation, and the broader democratic process. While the challenges are vast, the episode offers potential paths forward, such as enhancing platform accountability, fostering information literacy, and scrutinizing AI's role in the information ecosystem. Ultimately, the message is clear: passive consumption has risks, and active, critical engagement with information is essential for a more informed society.

Tuesday May 27, 2025

Competing in the Age of AI by Marco Iansiti and Karim R. Lakhani examines how artificial intelligence is fundamentally reshaping businesses, covering how companies are being transformed by digital networks and the need for swift adaptation to thrive in this new economic age. The book highlights how value creation and capture are changing and discusses crucial ethical considerations related to AI, such as bias and privacy. It also explores the shift to digital operating models and the obstacles organizations face in adapting their architectures and technology to remain competitive in the digital landscape. Overall, the text offers a guide for leaders on leveraging AI for transformation, growth, and innovation.

Sunday May 25, 2025

Cybersecurity Oversight by BoardsBoards of directors must evolve their approach to cybersecurity, recognizing it as a critical business risk. Traditional views treated it as a mere IT problem, but research has revealed the need for serious attention from the highest levels. This includes making cybersecurity a routine item on the board’s agenda and understanding its broader organizational implications.
 
 

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